Chicken Alfredo Lasagna

This Chicken Alfredo Lasagna is a make ahead friendly dish that’s perfect for entertaining. Just add a tossed salad and crusty bread for a complete meal that’s full of rich and delicious flavor.

This lasagna is a great recipe to have in your back pocket. Pre-cooked chicken and no-boil noodles make the prep work a snap. A creamy homemade alfredo sauce comes together quickly and is crazy good. 

Then the whole casserole can be assembled and refrigerated until you’re ready to bake it. It serves up to 12 people which makes it great for entertaining.

Ingredients Needed to Make this Recipe

Full instructions can be found below in the recipe card

• Rotisserie chicken or cooked chicken breast meat
• No-boil lasagna noodles
• Zucchini
• Red bell Pepper
• Fresh spinach
• Homemade alfredo sauce which consists of whole milk, butter, flour Italian blend shredded cheese and dried oregano
• Garlic
• Shredded mozzarella
• Feta cheese

What to Serve with Chicken Lasagna

• This Field Greens Salad is a simple salad that is perfect with this lasagna.
• These copy cat  Olive Garden bread sticks are also a great accompaniment.
• A glass of your favorite chardonnay pairs really well with this casserole.

More Lasagna Recipes to Try

• Easy Traditional Lasagna
• Tex-Mex Lasagna
• Zucchini Lasagna Roll-Ups
• Lazy Day Chicken Lasagna

FAQs

Can I use jarred Alfredo sauce for this lasagna?

The homemade sauce is definitely preferred, but jarred sauce can be used if you’re pinched for time. I would suggest adding dried oregano and some garlic powder to bump up the flavor.  

Is chicken alfredo lasagna a freezer friendly dish?

Once the lasagna is assembled it can be frozen. Cover the baking dish with foil and freeze for up to  one month. When you’re ready to bake, defrost completely before baking and then bake according to instructions. Be aware that you may need to add some additional cooking time, up to an additional 15 minutes.

Can frozen spinach be used in place of fresh?

I recommend using fresh spinach, but if frozen is what you have on hand it can be used. Use one box that’s been defrosted and make sure that you squeeze all of the extra moisture out of it.          

Continue to Content

Yield: 12

Chicken Alfredo Lasagna

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This Chicken Alfredo Lasagna is a make ahead friendly dish that's perfect for entertaining. Just add a tossed salad and crusty bread for a complete meal that's full of rich and delicious flavor.

Prep Time 30 minutes

Cook Time 45 minutes

Additional Time 15 minutes

Total Time 1 hour 30 minutes

Ingredients

• 6 no-boil lasagna noodles
• 2 tbsp butter
• 2 tbsp flour
• 2 1/4 cups milk, divided
• pinch of nutmeg
• 3 oz shredded Italian blend cheese
• 1/2 tsp salt
• 1/2 tsp pepper
• 1 tsp dried oregano
• 3 cups chopped cooked chicken
• 1/2 cup zucchini, chopped
• 1/2 cup red bell pepper, chopped
• 1/4 cup red onion, finely chopped
• 2 cloves garlic, minced
• 3 cups shredded mozzarella
• 4 oz crumbled feta cheese
• 2 packed cups fresh baby spinach

Instructions

1. Melt butter in a large skilled over medium hea
2. Once butter is melted, whisk in flour and allow to cook for a minute.
3. Whisking constantly, slowly add 2 cups of milk.
4. Continue whisking and allow to come to a bubble and cook until mixture starts to thicken.
5. Stir in nutmeg.
6. At this point, turn the heat off and stir in the Italian blend cheese, about 1/3 at a time until it’s melted.
7. Stir in salt and pepper to taste.
8. Set sauce aside and allow to cool.
9. In a large bowl, thoroughly combine chicken, zucchini, red pepper, onion, garlic and mozzarella and feta cheeses.
10. In a smaller bowl, combine sauce with remaining 1/4 cup milk and oregano.
11. To assemble lasagna, spread 2/3 cup of the alfredo sauce mixture in the bottom of a 9 x 13 pan.
12. Top with 3 lasagna noodles.
13. Layer half of the spinach leaves over noodles.
14. Top with half of the chicken mixture.
15. Repeat layers, starting with half the remaining sauce spread over the chicken mixture, then noodles, spinach, chicken mixture and remaining sauce.
16. Cover with aluminum foil and bake at 375 degrees for 45 minutes.
17. Remove foil and bake for an additional 15 minutes, until bubbly.
18. Remove from oven, loosely cover with foil and let stand for 15 minutes.
19. Cut into 12 squares and serve.

Nutrition Information:

Yield:

12

Serving Size:

1
Amount Per Serving: Calories: 290Total Fat: 16gSaturated Fat: 8gTrans Fat: 0gUnsaturated Fat: 6gCholesterol: 70mgSodium: 440mgCarbohydrates: 16gFiber: 1gSugar: 4gProtein: 20g